is a zeotropic hydrofluorocarbon blend of R-32, R-125, and R-134a. The R-32 serves to provide the heat capacity, R-125 decreases flammability, R-134a reduces pressure.R-407c is a mixture of hydrofluorocarbons used as a refrigerant. It is a zeotropic blend of difluoromethane (R-32), pentafluoroethane (R-125), and 1,1,1,2-tetrafluoroethane (R-134a). Difluoromethane serves to provide the heat capacity, pentafluoroethane decreases flammability, tetrafluoroethane reduces pressure.

R410A- has replaced R-22, R-410A is a zeotropic, but near-azeotropic mixture of difluoromethane (CH2F2, called R-32) and pentafluoroethane (CHF2CF3, called R-125), which is used as a refrigerant in air conditioning applications.

is a HFC "nearly azeotropic" blend of 52 wt.% R-143a, 44 wt.% R-125, and 4 wt.% R-134a. It is designed as a replacement of R-22 and R-502 CFC. Its boiling point at normal pressure is -46.5 °C, its liquid density is 0.485 g/cm3.

R-134a is a haloalkane refrigerant with thermodynamic properties similar to R-12 (dichlorodifluoromethane), but with less ozone depletion potential. It has the formula CH2FCF3, and a boiling point of −26.3 °C (−15.34 °F) at atmospheric pressure.